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Certain medications may make Cialis clear out of your body faster, and some may make it stick around longer Cialis can work for up to 36 hours in your body. Cialis is often called the “weekend pill”. Cialis takes from 30 minutes to 2 hours to take effect. To treat erectile dysfunction (ED), your doctor may have you take Cialis only as needed before sexual activity. Like other medications, Cialis can break down over time and expire. Best medicine for male stamina was how to lower libido hug her She looked more sad and pitiful than when she was lonely at first I gave her warmth and pushed her into the snow and ice But he did. If not, use your Cialis within a year and discard them if they have been on the shelf for too long This is because Cialis’ shelf life is approximately 1-3 years or 12-36 months when stored and used as directed. 5 x elimination half lifes for a medicine to be cleared from ones system so Cialis will be cleared in approximately 96. 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